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  • NYU Dataset

    Brain Insulin Resistance in Subjects with Major Depressive Disorder

    Authors
    Carla Nasca
    Josh Dobbin
    Benedetta Bigio
    Kathleen Watson
    9 more author(s)...
    Description

    Previous studies in rodent showed impaired brain insulin signaling with resultant insulin resistance (IR) modulates synaptic plasticity and the corresponding behavioral functions. This study investigated whether brain enriched exosomes and brain IR differ between subjects with major depressive disorder (MDD) and respective controls. They also examined potential sex differences in circulating brain...

    Subject
    Neuroscience
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