NYU Health Sciences Library NYU Data Catalog
NYU Health Sciences Library NYU Data Catalog
NYU Health Sciences Library Data Catalog

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Results Found: 2
  • NYU Dataset

    Brain Insulin Resistance in Subjects with Major Depressive Disorder

    Authors
    Carla Nasca
    Josh Dobbin
    Benedetta Bigio
    Kathleen Watson
    9 more author(s)...
    Description

    Previous studies in rodent showed impaired brain insulin signaling with resultant insulin resistance (IR) modulates synaptic plasticity and the corresponding behavioral functions. This study investigated whether brain enriched exosomes and brain IR differ between subjects with major depressive disorder (MDD) and respective controls. They also examined potential sex differences in circulating brain...

    Subject
    Neurosciences
    Access Rights
    Application Required
    Author Approval Required
  • NYU Dataset

    Insulin Signal Is Required for Sensory Neuron Development in Caenorhabditis elegans

    Authors
    Lauren Bayer Horowitz
    Julia P. Brandt
    Niels Ringstad
    Description

    Caenorhabditis elegans (C. elegans) is a powerful model for the study of nervous system development. This study investigated mechanisms required for the development of C. elegans sensory neurons, BAGs. C. elegans express many insulin-like peptides (ILPs), which are released from BAGs, throughout the nervous system. It is found that the p38 MAP kinase PMK-3 that is required for the differentiation of...

    Subject
    Genomics
    Neurosciences
    Access Rights
    Free to All