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  • NYU Dataset

    Augmentation of Parasympathetic Signaling with Pyridostigmine in Heart Failure

    Alternate Title(s)
    APP-HF
    Authors
    Randal Goldberg
    Lucy Norcliffe-Kauffman
    Ikoa Jeschke-Lopez
    Yu Guo
    8 more author(s)...
    Description

    This dataset was collected during a prospective phase 2 double-blind randomized placebo-controlled a dose-finding clinical trial to compare the effects of three ascending doses of pyridostigmine (15, 30, and 60 mg three times daily) vs. matching placebo on post-exercise heart rate recovery and other measures of sympathovagal balance. The study included four stages: Screening, randomization, and baseline...

    Subject
    Chronic Disease
    Health Status
    Risk Factors
    Access Rights
    Application Required
    Author Approval Required
  • NYU Dataset

    Development of Long-Term Vagus Nerve Stimulation in Mouse Model

    Authors
    Ibrahim T. Mughrabi
    Jordan Hickman
    Naveen Jayaprakash
    Dane Thompson
    13 more author(s)...
    Description

    This study developed a scalable model for long-term vagus nerve stimulation (VNS) in mice. For this study, C57BL/6 mice were used in all experiments. The dataset includes histology and immunohistochemistry data as well as supplementary data tied to the publication. The supplementary data includes data that was used to assemble different figures in the publication, which contains data about heart rate...

    Subject
    Chronic Disease
    Neuroscience
    Access Rights
    Free to All