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NYU Dataset
Augmentation of Parasympathetic Signaling with Pyridostigmine in Heart Failure
- Alternate Title(s)
- APP-HF
- Authors
- Randal GoldbergLucy Norcliffe-KauffmanIkoa Jeschke-LopezYu Guo8 more author(s)...
- Description
This dataset was collected during a prospective phase 2 double-blind randomized placebo-controlled a dose-finding clinical trial to compare the effects of three ascending doses of pyridostigmine (15, 30, and 60 mg three times daily) vs. matching placebo on post-exercise heart rate recovery and other measures of sympathovagal balance. The study included four stages: Screening, randomization, and baseline...
- Subject
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Chronic DiseaseHealth StatusRisk Factors
- Access Rights
- Application RequiredAuthor Approval Required
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NYU Dataset
Development of Long-Term Vagus Nerve Stimulation in Mouse Model
- Authors
- Ibrahim T. MughrabiJordan HickmanNaveen JayaprakashDane Thompson13 more author(s)...
- Description
This study developed a scalable model for long-term vagus nerve stimulation (VNS) in mice. Male C57BL/6 mice were instrumented with implanted ECG electrodes to measure heart rate threshold in conscious animals. In awake experiments, animals implanted with ECG leads were gently restrained and connected to a commutator that interfaced with the stimulus generator and the bio-amplifier. The dataset includes...
- Subject
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Neurosciences
- Access Rights
- Free to All