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  • NYU Dataset

    Glucose Transporter 1 is Essential to Maintain Brain Endothelial Cell Homeostasis Under Hyperglycemia Condition

    Authors
    Benjamin Miao
    Mohammad Sarif Mohiuddin
    Rashu Barua
    Md Wahiduzzaman
    6 more author(s)...
    Description

    Glucose transporter-1 (GLUT1) is known for regulating glucose uptake in brain endothelial cells. This study demonstrated the importance of GLUT1 in preserving brain endothelial cell homeostasis beyond regulating glucose uptake. Bulk RNA sequencing was used to analyze transcriptomic alterations under hyperglycemia and GLUT1 deficiency conditions to elucidate the GLUT1-mediated protective mechanism....

    Subject
    Genomics
    Access Rights
    Free to All