NYU Data Catalog

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  • NYU Dataset

    Inhibitory Co-Transmission From Midbrain Dopamine Neurons Relies on Presynaptic GABA Uptake

    Authors
    Riccardo Melani
    Nicolas X. Tritsch
    Description

    Dopamine releasing neurons in the substantia nigra pars compacta inhibit target cells in the striatum through postsynaptic activation of γ-aminobutyric acid (GABA) receptors. However, the molecular mechanisms responsible for GABAergic signaling remains unknown. This study found that inhibitory co-transmission from midbrain dopaminergic neurons does not depend on cell-autonomous GABA synthesis, but...

    Subject
    Neuroscience
    Access Rights
    Free to All
  • NYU Dataset

    GABA Decrease is Associated With Degraded Neural Specificity in the Visual Cortex of Glaucoma Patients

    Authors
    Ji Won Bang
    Carlos Parra
    Kevin Yu
    Gadi Wollstein
    2 more author(s)...
    Description

    To investigate the GABAergic and glutamatergic systems and neural specificity in the visual cortex of glaucoma patients, the research team recruited 40 patients with glaucoma (14 with early glaucoma and 16 with advanced glaucoma) and 24 age-matched healthy subjects to undergo clinical ophthalmic exams and magnetic resonance imaging (MRI) with fixation tasks. Researchers obtained the following data: Structural...

    Subject
    Anatomy
    Chronic Disease
    Neuroscience
    Access Rights
    Free to All