NYU Data Catalog

Filter by

of 1 Next >
Results Found: 2
  • NYU Dataset

    Brain Insulin Resistance in Subjects with Major Depressive Disorder

    Authors
    Carla Nasca
    Josh Dobbin
    Benedetta Bigio
    Kathleen Watson
    9 more author(s)...
    Description

    Previous studies in rodent showed impaired brain insulin signaling with resultant insulin resistance (IR) modulates synaptic plasticity and the corresponding behavioral functions. This study investigated whether brain enriched exosomes and brain IR differ between subjects with major depressive disorder (MDD) and respective controls. They also examined potential sex differences in circulating brain...

    Subject
    Neuroscience
    Access Rights
    Application Required
    Author Approval Required
  • NYU Dataset

    Defensosomes Serve as Decoys to Inhibit SARS-CoV-2 Infection

    Authors
    Krystal L. Ching
    Maren de Vries
    Juan Gago
    Kristen Dancel-Manning
    12 more author(s)...
    Description

    Exosomes mediate intercellular communication by transporting substrates with a variety of functions related to tissue homeostasis and disease. Recently, a subset of exosomes was labeled as defensosomes that are assembled during bacterial infection. Defensosomes mediate host defense by binding and inhibiting pore-forming toxins secreted by bacterial pathogens through incorporating protein receptors...

    Subject
    COVID-19
    Genomics
    Infectious Disease
    Access Rights
    Free to All