NYU Data Catalog

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  • NYU Dataset

    RNA Recognition Mechanism that Governs Np4 Decapping by RppH

    Authors
    Rose Levenson-Palmer
    Daniel J. Luciano
    Nikita Vasilyev
    Ashok Nuthanakanti
    2 more author(s)...
    Description

    Dinucleoside tetraphosphates have been shown to function in bacteria as precursors to nucleoside tetraphosphate (Np4) RNA caps. The removal of this cap is critical for initiating 5′ end-dependent degradation of those RNAs, which affects bacterial adaptability to stress. This study described that the RNA pyrophosphohydrolase (RppH) assumes a leading role in decapping those transcripts in Escherichia...

    Subject
    Proteomics
    Access Rights
    Free to All
  • NYU Dataset

    Pathogen-Specific Gut Microbiomes Associated with Inflammatory Bowel Disease Outcomes

    Authors
    Jordan E. Axelrad
    Ze Chen
    Joseph C. Devlin
    Kelly V. Ruggles
    1 more author(s)...
    Description

    This study identified the gut microbiome during an acute enteric infection in patients with and without inflammatory bowel disease (IBD). A cross-sectional study was performed on 260 patients who underwent stool testing and tested positive for Clostridioides difficile, Escherichia coli, or norovirus, or negative for all pathogens, and 25 healthy controls. They collected the following data from the...

    Subject
    Chronic Disease
    Genomics
    Health Status
    Population Characteristics
    Risk Factors
    Surgery
    Access Rights
    Application Required
    Author Approval Required
  • NYU Dataset

    Energy Coupling and Stoichiometry of Zn2+/H+ Antiport by YiiP

    Authors
    Adel Hussein
    Shujie Fan
    Maria Lopez-Redondo
    Ian Kenney
    3 more author(s)...
    Description

    Previous studies of YiiP, bacterial Zn2+/H+ antiporter, have shown a homodimeric architecture and the presence of three distinct Zn2+ binding sites. YiiP is a representative of the cation diffusion facilitator superfamily, which are responsible for homeostasis of transition metal ions. This study used cryo-electron microscopy, microscale thermophoresis, and molecular dynamics simulations to address...

    Subject
    Proteomics
    Access Rights
    Free to All