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  • NYU Dataset

    Lateral Entorhinal Cortex Inputs Modulate Hippocampal Dendritic Excitability

    Authors
    Olesia M. Bilash
    Spyridon Chavlis
    Cara D. Johnson
    Panayiota Poirazi
    1 more author(s)...
    Description

    Lateral entorhinal cortex (LEC) performs important functions for episodic memory processing and coding for contextually salient elements of an environment or experience. This study combined functional circuit mapping and computational modeling to examine the cellular and circuit mechanisms by which long-range glutamatergic LEC projections influence the local activity in the hippocampus. This dataset...

    Subject
    Neuroscience
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    Author Approval Required
  • NYU Dataset

    Subcellular Population Imaging Tools Reveal Stable Apical Dendrites in Hippocampal Area CA3

    Authors
    Jason J. Moore
    Shannon K. Rashid
    Emmett Bicker
    Cara D. Johnson
    3 more author(s)...
    Description

    This study imaged in vivo calcium signals from soma, apical dendrites, and basal dendrites in mouse hippocampal CA3 pyramidal neurons during head-fixed navigation to demonstrate apical and basal dendrites of pyramidal neurons receive anatomically and functionally distinct inputs. Computational tools were developed to automatically segment dendrites and extract accurate fluorescence traces from densely...

    Subject
    Neuroscience
    Access Rights
    Free to All