NYU Data Catalog

Filter by

of 1 Next >
Results Found: 2
  • NYU Dataset

    Hyperactive CDK2 Activity in Basal-like Breast Cancer Imposes a Genome Integrity Liability

    Authors
    Vladislav O. Sviderskiy
    Lili Blumenberg
    Elizabeth Gorodetsky
    Triantafyllia Karakousi
    13 more author(s)...
    Description

    This study showed that basal-like breast cancer (BLBC) is sensitive to suppression of iron-sulfur cluster (ISC) biosynthesis and identified DNA polymerase epsilon (POLE) as an ISC-containing protein that underlies this phenotype. This dataset includes primary RNA sequencing data and other primary data, as well as supplementary data tied to the publication. The supplementary data contains tables, which...

    Subject
    Genomics
    Access Rights
    Free to All
  • NYU Dataset

    Elongin A Regulates Transcription In Vivo Through Enhanced RNA Polymerase Processivity

    Authors
    Yating Wang
    Liming Hou
    M. Behfar Ardehali
    Robert E. Kingston
    1 more author(s)...
    Description

    Elongin, an RNA polymerase II (RNAPII)-associated factor, has shown to stimulate transcriptional elongation in vitro. The Elongin complex is assumed to be required for transcriptional induction in response to cellular stimuli. However, the role of this complex during transcription has not been studied in vivo. This study performed comprehensive studies of the role of Elongin A, the largest subunit...

    Subject
    Genomics
    Access Rights
    Free to All