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  • NYU Dataset

    Calreticulin Accelerates Corneal Wound Closure and Mitigates Fibrosis

    Authors
    Sarita Mishra
    Miguel A. Manzanares
    Justin Prater
    David Culp
    1 more author(s)...
    Description

    Previous studies demonstrated that topically applied calreticulin (CALR) healed full‐thickness excisional animal wounds by a tissue regenerative process markedly enhancing repair without evoking angiogenesis. This study applied CALR in a rabbit corneal injury model. They accelerated full wound closure by 3 days and delayed healing caused by corticosteroids by 6 days. In addition, healed wounds without...

    Subject
    Anatomy
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