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  • NYU Dataset

    Calreticulin Accelerates Corneal Wound Closure and Mitigates Fibrosis

    Authors
    Sarita Mishra
    Miguel A. Manzanares
    Justin Prater
    David Culp
    1 more author(s)...
    Description

    Previous studies demonstrated that topically applied calreticulin (CALR) healed full‐thickness excisional animal wounds by a tissue regenerative process markedly enhancing repair without evoking angiogenesis. This study applied CALR in a rabbit corneal injury model. They accelerated full wound closure by 3 days and delayed healing caused by corticosteroids by 6 days. In addition, healed wounds without...

    Subject
    Anatomy
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    Author Approval Required
  • NYU Dataset

    Single Cell RNA Sequencing of Human Cornea Organoids Identifies Cell Fates

    Authors
    George Maiti
    Maithe Rocha Monteiro de Barros
    Nan Hu
    Igor Dolgalev
    5 more author(s)...
    Description

    The cornea is the outermost transparent layer of the eye that serves as a protective barrier and studying the cornea can be crucial for understanding human corneal diseases. Although several studies have examined the single-cell transcriptomic composition of the human cornea, its organoids have not been examined similarly. This study explained the transcriptomic cell fate of human cornea organoids...

    Subject
    Anatomy
    Genomics
    Access Rights
    Free to All