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  • NYU Dataset

    Human Hepatoma Huh-7 Cell Culture Models Deficient in Apolipoprotein B Secretion

    Authors
    Swati Valmiki
    Sara Rosario
    Ashley Mooring
    Chandana Prakashmurthy
    7 more author(s)...
    Description

    Apolipoprotein B (apoB) is an essential structural protein for the assembly and secretion of triglyceride-rich lipoproteins. Inhibition of apoB and microsomal triglyceride transfer protein (MTP) decreases plasma lipid levels but at a risk of lipid accumulation in tissues. To understand the global consequences of APOB gene deficiency, a human hepatoma (Huh-7) cell culture model system deficient in apoB...

    Subject
    Genomics
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