-
NYU Dataset
Multi-Contrast MRI of the Mouse Brain Estimates Histological Staining Intensity
- Authors
- Zifei LiangChoong H. LeeTanzil M. ArefinZijun Dong6 more author(s)...
- Description
Magnetic resonance imaging (MRI) can image brain structure non-invasively and without ionizing radiation. However, inferring histopathological information from MRI remains challenging due to lack of direct links between MRI signals and cellular structures. This study showed that deep convolutional neural networks can estimate histological staining intensity directly from MRI signals developed using...
- Subject
-
AnatomyNeurosciences
- Access Rights
- Free to All
-
NYU Dataset
Synaptic Vesicle Traffic is Supported by Transient Actin Filaments
- Authors
- Nicolas ChenouardFeng XuanRichard W. Tsien
- Description
Synaptic vesicles (SVs) play a key role in synaptic transmission. This study used time-lapse microscopy to demonstrate two distinct mechanisms of vesicle traffic along axons. They employed specific pharmacological interventions along with imaging of transient actin polymerization and traffic of recycling SVs loaded with single quantum dots to characterize the underlying axonal actin structures. For...
- Subject
-
Neurosciences
- Access Rights
- Application RequiredAuthor Approval Required
-
NYU Dataset
Scattering Approach to Diffusion Quantifies Axonal Damage in Brain Injury
- Authors
- Ali AbdollahzadehRicardo Coronado-LeijaHong-Hsi LeeAlejandra Sierra2 more author(s)...
- Description
This study demonstrated that time-dependent diffusion MRI can detect subtle axonal changes in brain injury by identifying structural signatures of diffusive dynamics of water along axons. Scattering theory reveal two parameters that determine the diffusive dynamics of water along axons: the average reciprocal cross-section and the variance of long-range cross-sectional fluctuations. This theoretical...
- Subject
-
Neurosciences
- Access Rights
- Free to All