NYU Data Catalog

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  • NYU Dataset

    Early-Life Antibiotic Exposures Increase Susceptibility to Inflammatory Bowel Disease

    Authors
    Ceren Ozkul
    Victoria E. Ruiz
    Thomas Battaglia
    Joseph Xu
    4 more author(s)...
    Description

    The data from this study shows that early-life antibiotic use may affect the progression of subsequent disease conditions by changing host microbiota and immunologic development. For this study, they used a murine model of dextran sodium sulfate (DSS)-induced colitis and evaluated the effect on disease outcomes of early-life pulsed antibiotic treatment (PAT). The dataset includes 16S sequencing data....

    Subject
    Genomics
    Access Rights
    Free to All
  • NYU Dataset

    Early-Life Antibiotic Exposure Alters Intestinal Microbiome Composition

    Authors
    Timothy C. Borbet
    Miranda B. Pawline
    Jackie Li
    Melody L. Ho
    11 more author(s)...
    Description

    Early-life antibiotic exposures during postnatal development have lasting effects on microbiota composition. Previous studies in humans and mice have found altered microbial composition to be associated with enhanced disease susceptibility and modified immune status. They investigated impact of timing of antibiotic exposure by treating 5 to 9 days C57BL/6J mice with two of the most commonly prescribed...

    Subject
    Genomics
    Access Rights
    Free to All