-
NYU Dataset
Direct RNA Sequencing Reveals the Role of N6-Methyladenosine in Regulating Splicing of a Viral Pathogen
- Authors
- Alexander M. PriceKatharina E. HayerAlexa B. R. McIntyreNandan S. Gokhale7 more author(s)...
- Description
Adenovirus is a nuclear replicating DNA virus that relies on the host cell machinery for productive infection. Processing and metabolism of cellular RNAs are regulated by METTL3, which catalyzes the addition of N6-methyladenosine (m6A) to messenger RNAs. Although m6A-modified adenoviral RNAs have been detected previously, the location and function of m6A within the infectious cycle is unknown. For...
- Subject
-
GenomicsInfectious DiseaseProteomics
- Access Rights
- Free to All
