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  • NYU Dataset

    Synaptic Vesicle Traffic is Supported by Transient Actin Filaments

    Authors
    Nicolas Chenouard
    Feng Xuan
    Richard W. Tsien
    Description

    Synaptic vesicles (SVs) play a key role in synaptic transmission. This study used time-lapse microscopy to demonstrate two distinct mechanisms of vesicle traffic along axons. They utilized specific pharmacological interventions along with imaging of transient actin polymerization, and traffic of recycling SVs loaded with single quantum dots to characterize the underlying axonal actin structures. For...

    Subject
    Neuroscience
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