NYU Data Catalog

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  • NYU Dataset

    Cholinergic Suppression of Hippocampal Sharp-Wave Ripples Impairs Working Memory

    Authors
    Yiyao Zhang
    Liang Cao
    Viktor Varga
    Miao Jing
    3 more author(s)...
    Description

    Learning and memory are presumed to be supported by mechanisms that involve cholinergic transmission and hippocampal theta. This study examined the effect of sustained cholinergic activation on memory performance. For this study, they used G protein-coupled receptor activation based acetylcholine sensor to monitor acetylcholine activity during memory performance in mice. The dataset contains behavioral,...

    Subject
    Neuroscience
    Access Rights
    Free to All
  • NYU Dataset

    Interaction of Acetylcholine and Oxytocin Neuromodulation in the Hippocampus

    Authors
    Yiyao Zhang
    Mursel Karadas
    JingJing Liu
    Xinyi Gu
    4 more author(s)...
    Description

    This study examined the interaction of acetylcholine (ACh) and oxytocin (OXT) at slow and fast timescales during various brain states. They used simultaneous fiber-photometric measurements of ACh and OXT variations in the hippocampus using G-protein-coupled receptor activation-based Ach and OXT sensors. These optical measurements were compared with sleep-wake changes and characteristic brain-state-dependent...

    Subject
    Neuroscience
    Access Rights
    Free to All