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NYU Dataset
Cholinergic Suppression of Hippocampal Sharp-Wave Ripples Impairs Working Memory
- Authors
- Yiyao ZhangLiang CaoViktor VargaMiao Jing3 more author(s)...
- Description
Learning and memory are presumed to be supported by mechanisms that involve cholinergic transmission and hippocampal theta. This study examined the effect of sustained cholinergic activation on memory performance. For this study, they used G protein-coupled receptor activation based acetylcholine sensor to monitor acetylcholine activity during memory performance in mice. The dataset contains behavioral,...
- Subject
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Neurosciences
- Access Rights
- Free to All
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NYU Dataset
Interaction of Acetylcholine and Oxytocin Neuromodulation in the Hippocampus
- Authors
- Yiyao ZhangMursel KaradasJingJing LiuXinyi Gu4 more author(s)...
- Description
This study examined the interaction of acetylcholine (ACh) and oxytocin (OXT) at slow and fast timescales during various brain states. They used simultaneous fiber-photometric measurements of ACh and OXT variations in the hippocampus using G-protein-coupled receptor activation-based Ach and OXT sensors. These optical measurements were compared with sleep-wake changes and characteristic brain-state-dependent...
- Subject
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Neurosciences
- Access Rights
- Free to All
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NYU Dataset
Voluntary Exercise Increases Striatal Dopamine Release and Improves Motor Performance in Aging Mice
- Authors
- Guendalina BastioliMaria ManciniJyotiben C. PatelBegona Gamallo-Lana3 more author(s)...
- Description
This study evaluated the influence of physical exercise on striatal dopamine release, as well as on mobility and motor coordination in aging male and female C57BL/6J mice (46-52 weeks of age). Mice were allowed unlimited access to a freely rotating wheel (runners) or a locked wheel (controls) for 30 days. Electrically evoked dopamine release was quantified using fast-scan cyclic voltammetry, in the...
- Subject
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Neurosciences
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- Application RequiredAuthor Approval Required