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  • NYU Dataset

    NOGOB Receptor Deficiency Increases Cerebrovascular Permeability and Hemorrhage

    Authors
    Zhi Fang
    Xiaoran Sun
    Xiang Wang
    Ji Ma
    6 more author(s)...
    Description

    Cerebral cavernous malformation (CCM) lesions are caused by loss of function of CCM genes. Previous study showed that NOGOB receptor (NGBR) knockout in endothelial cells results in cerebrovascular lesions in the mouse embryo. However, the molecular mechanism by which NGBR regulates CCM1/2 expression has not been explained. This study used RNA sequencing analysis to determine the alteration of transcriptomic...

    Subject
    Genomics
    Access Rights
    Free to All