This dataset is composed of eight bilateral silicon-probe multi-cellular electrophysiological recordings performed on four male Long-Evans rats. These recordings were performed to assess the effect of novel spatial learning on hippocampal CA1 neural firing and LFP patterns in naïve animals. Each session consisted of a long (~4 hour) PRE rest/sleep epoch home-cage recordings performed in a familiar...

The data set contains recordings made from multiple anterior thalamic nuclei, mainly the antero-dorsal (AD) nucleus, and subicular areas, mainly the post-subiculum (PoS), in freely moving mice. Thalamic and subicular electrodes yielding high number of the so-called Head-Direction (HD) cells were likely to be located in the AD nucleus and the PoS, respectively. Electrode placement was confirmed by histology....

The data set contains multichannel simultaneous recordings made from layer CA1 of the right dorsal hippocampus of three Long-Evans rats during open field tasks in which the animals chased randomly placed drops of water or pieces of Froot Loops while on an elevated square platform. In order to examine the temporal relationships between theta oscillations and the coordination of neuronal firing in the...

This dataset of multi single neuron recordings was acquired from three rats (EE, FF, GG) while they performed a working memory task. Neuronal activity was monitored simultaneously in the PFC (64 channels) and the intermediate CA1 (32 channels) of the hippocampus. In one rat (EE), sleep was also recorded before and after the task. The data was obtained during 52 main recording sessions and nine short...

This data collection includes neural recordings obtained from the visual cortex (V1 and V2) and prearcurate gyrus (8Ar) of macaque monkeys (Macaca nemestrina and Macaca mulatta) during a direction discrimination task and code for replicating the modeling of neural representations. 96-channel microelectrode Utah arrays were implanted across the border of the V1 and V2 visual cortices of Macaca nemestrina....

Using a Y-shaped maze, several experiments were developed to assess conditions of associative learning among fruit fly larvae. Prior to the start of the experiments, some fruit fly larvae were fed a diet of all-trans-retinal (ATR), which is a co-factor for csChrimson activation (eliciting escape behavior in flies which perceive red light). A subgroup of larvae who were fed ATR also received cycloheximide...

Social interactions strongly impact the brain and the body. However, high-resolution descriptions of these important physical interactions and their neural correlates are lacking. This study described a hardware/software system and analysis pipeline that combines 3D videography, deep learning, physical modeling, and GPU-accelerated robust optimization with automatic analysis of neuronal receptive fields...

Exosomes mediate intercellular communication by transporting substrates with a variety of functions related to tissue homeostasis and disease. Recently, a subset of exosomes was labeled as defensosomes that are assembled during bacterial infection. Defensosomes mediate host defense by binding and inhibiting pore-forming toxins secreted by bacterial pathogens through incorporating protein receptors...

To develop the Primitive Sequencing pipeline (PrimSeq), a deep learning-based framework to automatically identify and count functional primitives in rehabilitation training, investigators captured the upper body motion of 41 chronic stroke patients aged 21 to 84 years old who performed a battery of rehabilitation activities. Eligibility criteria included premorbid right-handedness, ability to give...

This is a single-blind, two-site randomized clinical trial which evaluated the effectiveness of the Smart Beginnings model on early school readiness in low-income families. The Smart Beginnings intervention includes a Video Interaction Project (VIP), a 14-session universal primary prevention program delivered in the pediatric clinic at the time of well-child visits from birth through 36 months, and...