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  • Osteoarthritis Initiative

    Alternate Title(s)
    OAI
    Description

    The Osteoarthritis Initiative (OAI) was a longitudinal cohort study which investigated the natural history of knee osteoarthritis across the spectrum of the disease through the collection of imaging, biochemical, genetic, and risk markers of knee OA. Measures included knee symptoms and function (evaluated using the West Ontario and McMaster Universities Arthritis Index (WOMAC) and the Knee injury and...

    Subject
    Chronic Disease
    Health Status
    Risk Factors
    Access Rights
    Free to All
    Application Required
    Local Expert
    Cem Deniz
    Jonathan Samuels

  • Alzheimer’s Disease Neuroimaging Initiative

    Alternate Title(s)
    ADNI, ADNI1, ADNI GO, ADNI2, ADNI3
    Authors
    Michael W. Weiner
    Description

    The Alzheimer’s Disease Neuroimaging Initiative (ADNI) began in 2004 as longitudinal multicenter study to identify clinical, imaging, genetic, and biochemical biomarkers for the detection and tracking of Alzheimer’s disease (AD). Participants are recruited from and followed at 59 research sites in the United States and Canada. ADNI1 enrolled 400 subjects who were diagnosed with mild cognitive impairment...

    Subject
    Chronic Disease
    Genomics
    Mental Health
    Neuroscience
    Access Rights
    Free to All
    Application Required
    Author Approval Required
    Local Expert
    Omonigho M. Bubu
    Ricardo Osorio

  • Multicenter Osteoarthritis Study

    Alternate Title(s)
    MOST
    Authors
    Neil A. Segal
    Michael C. Nevitt
    K. Douglas Gross
    Jean Hietpas
    3 more author(s)...
    Description

    The Multicenter Osteoarthritis Study (MOST) is an ongoing longitudinal study which aims to identify novel and modifiable biomechanical factors (e.g., physical activity), bone and joint structural factors (assessed through knee MRI), and nutritional factors that are associated with the onset and progression of osteoarthritis (OA)-related knee symptoms and radiographic knee OA. A secondary aim is to...

    Subject
    Chronic Disease
    Risk Factors
    Access Rights
    Application Required
    Author Approval Required
    Local Expert
    Cem Deniz