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  • Osteoarthritis Initiative

    Alternate Title(s)
    OAI
    Description

    The Osteoarthritis Initiative (OAI) was a longitudinal cohort study which investigated the natural history of knee osteoarthritis across the spectrum of the disease through the collection of imaging, biochemical, genetic, and risk markers of knee OA. Measures included knee symptoms and function (evaluated using the West Ontario and McMaster Universities Arthritis Index (WOMAC) and the Knee injury and...

    Subject
    Chronic Disease
    Health Status
    Risk Factors
    Access Rights
    Free to All
    Application Required
    Local Expert
    Cem Deniz
    Jonathan Samuels
  • Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial Datasets

    Alternate Title(s)
    PLCO
    Description

    The Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial was a large randomized controlled trial that assessed whether certain screening practices decreased deaths from prostate, lung, colorectal and ovarian cancer. Approximately 155,000 men and women aged 55 to 74 years old were enrolled from 10 screening centers across the United States between November 1993 and July 2001. Participants...

    Subject
    Cancer
    Chronic Disease
    Health Care System
    Access Rights
    Application Required
    Local Expert
    Richard B. Hayes
  • Multicenter Osteoarthritis Study

    Alternate Title(s)
    MOST
    Authors
    Neil A. Segal
    Michael C. Nevitt
    K. Douglas Gross
    Jean Hietpas
    3 more author(s)...
    Description

    The Multicenter Osteoarthritis Study (MOST) is an ongoing longitudinal study which aims to identify novel and modifiable biomechanical factors (e.g., physical activity), bone and joint structural factors (assessed through knee MRI), and nutritional factors that are associated with the onset and progression of osteoarthritis (OA)-related knee symptoms and radiographic knee OA. A secondary aim is to...

    Subject
    Chronic Disease
    Risk Factors
    Access Rights
    Application Required
    Author Approval Required
    Local Expert
    Cem Deniz