NYU Health Sciences Library NYU Data Catalog
NYU Health Sciences Library NYU Data Catalog
NYU Health Sciences Library Data Catalog

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  • NYU Dataset

    Intra-Serotype Variation of Streptococcus pneumoniae Capsule

    Authors
    Hannes Eichner
    Cindy Wu
    Michael Cammer
    Elizabeth N. H. Tran
    3 more author(s)...
    Description

    Streptococcus pneumoniae (S. pneumoniae) remains a leading cause of respiratory and invasive diseases despite the availability of vaccines. These vaccines target a polysaccharide capsule the bacterium uses to evade the immune system. Variation of the capsule composition subdivides the organism into serotypes and influences its protective potency. It is commonly assumed that S. pneumoniae strains of...

    Subject
    Anatomy
    Infectious Disease
    Access Rights
    Free to All
  • NYU Dataset

    Mechanism of Beta-Arrestin 1 Mediated Src Activation via Src SH3 Domain

    Authors
    Natalia Pakharukova
    Brittany N. Thomas
    Harsh Bansia
    Linus Li
    12 more author(s)...
    Description

    Beta-arrestins (βarrs) are key transducers of G-protein coupled receptors, but the mechanisms of βarr signaling are poorly understood. Therefore, this study examined the structural mechanisms underlying βarr-mediated signal transduction. Using cryo-electron microscopy (cryo-EM), the study examined how βarr1 recruits and activates the non-receptor tyrosine kinase Src, a well-established signaling partner...

    Subject
    Proteomics
    Access Rights
    Free to All