NYU Data Catalog

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  • NYU Dataset

    SARS-CoV-2 infection triggers pro-atherogenic inflammatory responses in human coronary vessels

    Authors
    Natalia Eberhardt
    Maria G. Noval
    Ravneet Kaur
    Letizia Amadori
    19 more author(s)...
    Description

    This study combined multiple techniques (e.g., RNAscope in-situ hybridization, immunohistochemistry, immunofluorescence, single-cell RNA sequencing, bulk RNA sequencing, and functional assays) to investigate the inflammatory response associated with SARS-CoV-2 infection in human vascular tissues. Single cell RNA-sequencing data obtained from samples collected for this study is available via the Gene...

    Subject
    COVID-19
    Infectious Disease
    Risk Factors
    Access Rights
    Free to All
  • NYU Dataset

    Single-Cell Transcriptomics Identifies Gadd45b as a Regulator of Herpesvirus-Reactivating Neurons

    Authors
    Hui-Lan Hu
    Kalanghad P. Srinivas
    Shuoshuo Wang
    Moses V. Chao
    5 more author(s)...
    Description

    Single‐cell RNA sequencing (scRNA‐seq) has not been effectively used for exploring the interactions between the host cell and viral pathogens in latently infected cells. Therefore, this study used scRNA‐seq and single‐molecule sensitivity fluorescent in situ hybridization technologies to investigate host single‐cell transcriptome changes upon the reactivation of a human neurotropic virus, herpes simplex...

    Subject
    Genomics
    Access Rights
    Free to All