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NYU Dataset
Long-Term Imaging of Dorsal Root Ganglia in Awake Behaving Mice
- Authors
- Chao ChenJinhui ZhangLinlin SunYiling Zhang3 more author(s)...
- Description
The dorsal root ganglia (DRG) are the first-order neurons in the somatosensory system. However, DRG neuronal activity in awake behaving animals remains unknown. This study developed a method for imaging DRG at cellular and subcellular resolution over weeks in awake mice. In order to image DRG in the living mice, an intervertebral fusion mount was installed to reduce spinal movement and a vertebral...
- Subject
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Neurosciences
- Access Rights
- Free to All
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NYU Dataset
Insulin Signal Is Required for Sensory Neuron Development in Caenorhabditis elegans
- Authors
- Lauren Bayer HorowitzJulia P. BrandtNiels Ringstad
- Description
Caenorhabditis elegans (C. elegans) is a powerful model for the study of nervous system development. This study investigated mechanisms required for the development of C. elegans sensory neurons, BAGs. C. elegans express many insulin-like peptides (ILPs), which are released from BAGs, throughout the nervous system. It is found that the p38 MAP kinase PMK-3 that is required for the differentiation of...
- Subject
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GenomicsNeurosciences
- Access Rights
- Free to All
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NYU Dataset
Auditory Processing Remains Sensitive to Environmental Experience
- Authors
- Kelsey L. AnbuhlJustin D. YaoRobert A. HotzTodd M. Mowery1 more author(s)...
- Description
This study induced transient hearing loss (HL) spanning adolescence in jirds to determine whether behavioral and neural maturation are disrupted. A total of 46 Mongolian jirds (24 females and 22 males) were used in the study. To determine whether auditory function is vulnerable during adolescence, transient HL was induced with earplugs at postnatal day 23 (P23), after a well-defined auditory cortex...
- Subject
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Neurosciences
- Access Rights
- Free to All