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  • NYU Dataset

    Impairment of Visual Cortical Plasticity by Amyloid-Beta Species

    Authors
    Christopher M. William
    Matthew A. Stern
    Xuewei Pei
    Lubna Saqran
    3 more author(s)...
    Description

    Alzheimer’s disease (AD) is characterized by accumulation of amyloid-beta (Aβ) in amyloid plaques and transgenic and knock-in mice that express mutant alleles of amyloid precursor protein (APP) have been used to model the effects of Aβ. This study examined visual system plasticity in transgenic mice that express and secrete Aβ throughout the brain in the absence of APP overexpression to explore the...

    Subject
    Neuroscience
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