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NYU Dataset
IRG1–Itaconate Axis Protects From Cholesterol-Induced Inflammation and Atherosclerosis
- Authors
- Yannick CyrFazli K. BozalJose Gabriel Barcia DuranAlexandra A. C. Newman17 more author(s)...
- Description
Therapeutic approaches to reverse atherosclerotic inflammation are needed to address the rising global burden of cardiovascular disease (CVD). This study investigated therapeutic potential of the enzyme immune responsive gene 1 (IRG1) and its immunomodulatory product, itaconate for atherosclerosis in humans and mice. To investigate the expression of IRG1 in human atherosclerosis, single-cell RNA sequencing...
- Subject
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Genomics
- Access Rights
- Free to All