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NYU Dataset
Immune Responses Observed Before and After BNT162b2 mRNA Vaccine Administration in Individuals with and without History of SARS-CoV-2 Infection
- Authors
- Marie I. SamanovicAmber R. CorneliusSophie L. Gray-GaillardJoseph Richard Allen7 more author(s)...
- Description
To study and compare longitudinal immune responses to two-dose BNT162b2 mRNA vaccinations, investigators recruited 15 adults with a history of laboratory-confirmed COVID-19 and 21 adults who did not have COVID-19. Participants' ages ranged from 21 to 65 years old. Peripheral immune responses were assessed via blood samples drawn before and after each vaccine dose. A total of five samples were collected...
- Subject
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COVID-19Infectious Disease
- Timeframe
- 2021
- Access Rights
- Free to All
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NYU Dataset
mRNA COVID-19 vaccine elicits potent adaptive immune response without the acute inflammation of SARS-CoV-2 infection
- Authors
- Ellie IvanovaJasmine ShwetarJoseph C. DevlinTerkild B. Buus17 more author(s)...
- Description
To investigate immune responses to SARS-CoV-2 antigens under various inflammatory conditions, researchers collected blood samples from five adult patients seen at NYU Langone Health with lab-confirmed cases of acute COVID-19 and from nine healthy adults (seven who had received the BNT162b2 mRNA vaccine and two with no prior exposure to SARS-CoV-2). Samples were obtained at multiple time points. Patients...
- Subject
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COVID-19GenomicsInfectious Disease
- Access Rights
- Free to All
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NYU Dataset
Longitudinal study of immunity to SARS‐CoV2 in ocrelizumab‐treated MS patients up to 2 years after COVID‐19 vaccination
- Alternate Title(s)
- Vaccine‐generated Immunity in Ocrelizumab‐treated Patients: Longitudinal Assessments (VIOLA)
- Authors
- Ilya KisterRyan CurtinAmanda L. PiquetTyler Borko16 more author(s)...
- Description
This is a prospective, two-year study of immunity against SARS-CoV-2 in multiple sclerosis patients receiving ocrelizumab (OCR) at the time of COVID vaccination. Researchers recruited 60 patients (aged 18-65) from the NYU MS Comprehensive Care Center in New York City and the Rocky Mountain MS Center at the University of Colorado Anschutz Medical Center in Aurora, CO. Participants provided blood samples...
- Subject
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Chronic DiseaseCOVID-19
- Access Rights
- Free to All
