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  • NYU Dataset

    Genome-Wide Aryl Hydrocarbon Receptor-DNA Binding Reveal Tissue-Specific Binding Determinants

    Authors
    David Filipovic
    Wenjie Qi
    Omar Kana
    Daniel Marri
    4 more author(s)...
    Description

    Aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor whose ligands include the environmental contaminant 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Ligand-activated AhR binds to DNA at dioxin response elements (DREs). Most DREs in accessible chromatin are not bound by TCDD-activated AhR, and DREs accessible in multiple tissues can be bound in some and unbound in others. This...

    Subject
    Genomics
    Access Rights
    Free to All