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  • NYU Dataset

    Intra-axonal Space Segmentation from 3D Scanning Electron Microscopy (SEM) of the Mouse Brain Genu of Corpus Callosum

    Authors
    Hong-Hsi Lee
    Dmitry S. Novikov
    Els Fieremans
    Description

    This dataset includes 3D scanning electron microscopy (SEM) images of a female mouse corpus callosum and MATLAB code for random walker (RaW) segmentations of myelinated axons. The code additionally characterizes inner axonal diameters and fiber orientation dispersion within segments of the intra-axonal spaces and myelin sheaths. In the study, a female 8-week-old C57BL/6 mouse was perfused trans-cardiacally...

    Subject
    Anatomy
    Neurosciences
    Access Rights
    Free to All
  • NYU Dataset

    Scattering Approach to Diffusion Quantifies Axonal Damage in Brain Injury

    Authors
    Ali Abdollahzadeh
    Ricardo Coronado-Leija
    Hong-Hsi Lee
    Alejandra Sierra
    2 more author(s)...
    Description

    This study demonstrated that time-dependent diffusion MRI can detect subtle axonal changes in brain injury by identifying structural signatures of diffusive dynamics of water along axons. Scattering theory reveal two parameters that determine the diffusive dynamics of water along axons: the average reciprocal cross-section and the variance of long-range cross-sectional fluctuations. This theoretical...

    Subject
    Neurosciences
    Access Rights
    Free to All