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  • NYU Dataset

    Autoimmunity to Annexin A2 Predicts Mortality Among Hospitalised COVID-19 Patients

    Authors
    Marisol Zuniga
    Claudia Gomes
    Steven E. Carsons
    Michael T. Bender
    4 more author(s)...
    Description

    This study examined autoimmune antibodies to annexin A2, which is a phospholipid-binding protein expressed in the lung and other organs, in COVID-19 patients. Annexin A2 is critical for fibrinolysis, lung elasticity, cell membrane repair, and integrity of the pulmonary vasculature. Therefore, antagonism of annexin A2 may explain many of the clinical features of severe COVID-19 cases. This study analyzed...

    Subject
    COVID-19
    Infectious Disease
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