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  • NYU Dataset

    Behavioral data, fiber photometry recordings, in vitro recordings, and RNA-seq data from posterior amygdala in mice

    Authors
    Takashi Yamaguchi
    Dongyu Wei
    Soomin C. Song
    Byungkook Lim
    2 more author(s)...
    Description

    This dataset contains the following: video recordings of animal behaviors, RNA-seq analysis, in vitro recordings, and fiber photometry recordings for a study on the regulation by the posterior amygdala (PA) of sexual and aggressive behaviors in male mice. The video recordings are of all animal behaviors from two synchronized cameras on the side and top of the cage with frame by frame behavioral annotation...

    Subject
    Neuroscience
    Access Rights
    Free to All
  • NYU Dataset

    Effects of Early-Life Penicillin Exposure on the Gut Microbiome and Frontal Cortex and Amygdala Gene Expression

    Authors
    Angelina Volkova
    Kelly V. Ruggles
    Anjelique Schulfer
    Zhan Gao
    2 more author(s)...
    Description

    This study created an experimental model to assess the effects of early-life exposures to antibiotics on the intestinal microbiota and gene expression in the brain. For this study, C57BL/6 mice were breed for 5 days and the pregnant dams were randomized into 3 treatment groups. First group was treated with low-dose penicillin G in their drinking water starting during the last week of pregnancy and...

    Subject
    Neuroscience
    Access Rights
    Free to All
  • NYU Dataset

    Infant pain vs. pain with parental suppression: Immediate and enduring impact on brain, pain and affect

    Authors
    Gordon A. Barr
    Maya Opendak
    Rosemarie E. Perry
    Emma Sarro
    1 more author(s)...
    Description

    To investigate the impact of social buffering on pain, the study team administered mild tail shocks to infant rat pups at postnatal day (PN) 8 or 12, with or without their mothers. They hypothesized that repeated exposure to shock would alter their inflammatory pain responses as adults when experienced between PN5 and 9 (pain sensitive period prior to functional maturation of the amygdala), whereas...

    Subject
    Mental Health
    Neuroscience
    Access Rights
    Free to All
  • NYU Dataset

    Transcriptionally Defined Amygdala Subpopulations Play Distinct Roles in Innate Social Behaviors

    Authors
    Julieta E. Lischinsky
    Luping Yin
    Chenxi Shi
    Nandkishore Prakash
    5 more author(s)...
    Description

    Social behaviors, such as mating, fighting, and parenting, are innate and supported by dedicated neural circuits. However, the molecular identities of these circuits and how they are established developmentally and shaped by experience remain unknown. This study demonstrate that medial amygdala cells originating from two embryonically parcellated developmental lineages have distinct response patterns...

    Subject
    Neuroscience
    Access Rights
    Free to All