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  • NYU Dataset

    RNA Recognition Mechanism that Governs Np4 Decapping by RppH

    Authors
    Rose Levenson-Palmer
    Daniel J. Luciano
    Nikita Vasilyev
    Ashok Nuthanakanti
    2 more author(s)...
    Description

    Dinucleoside tetraphosphates have been shown to function in bacteria as precursors to nucleoside tetraphosphate (Np4) RNA caps. The removal of this cap is critical for initiating 5′ end-dependent degradation of those RNAs, which affects bacterial adaptability to stress. This study described that the RNA pyrophosphohydrolase (RppH) assumes a leading role in decapping those transcripts in Escherichia...

    Subject
    Proteomics
    Access Rights
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