Rehabilitation at Home Using Mobile Health for Older Adults Hospitalized for Ischemic Heart Disease: The RESILIENT Randomized Clinical Trial

Description

The Rehabilitation at Home Using Mobile Health in Older Adults After Hospitalization for Ischemic Heart Disease (RESILIENT) trial is a prospective, multicenter, randomized clinical trial. The main objective of RESILIENT was to evaluate whether a mobile health cardiac rehabilitation (mHealth-CR) intervention improved functional capacity compared with usual care among patients aged 65 or older with ischemic heart disease. The trial was conducted at five academic hospitals within four health systems. 400 participants were enrolled between 2020 and 2024, with 298 assigned to the intervention group and 102 assigned to the control (usual care) group.

Participants assigned to the study intervention received an mHealth-CR program consisting of mHealth-CR software (a commercially available product installed on a tablet computer provided for the duration of the trial), counseling by an exercise therapist, and remote physiologic monitoring; participants assigned to the control arm received a traditional ambulatory CR program. Counseling by the exercise therapist included an initial in-person visit and weekly remote counseling sessions conducted by telephone. Both programs took place for a duration of three months. Remote physiologic monitoring was obtained via an activity monitor and blood pressure cuff, both of which were connected via Bluetooth to the study tablet at the baseline visit.

The prespecified primary endpoint was change in 6MWD, measured by a 6-minute walk test (6MWT) at baseline and 3 months. Secondary endpoints included angina burden, general health status, activities of daily living (ADLs) and instrumental ADLs, and goal attainment. Safety end points included hospitalization for events during the intervention period that may have been related to home exercise, such as a fall or arrhythmia.

Timeframe

2020 - 2024

Geographic Coverage

Connecticut

Massachusetts

New York (State)

Subject of Study

Subject Domain

Health Status

Population Age

Senior (65 years - 79 years)

Aged (80 years and over)