NYU Dataset
Structure Prediction Modeling Characterized Guided Entry of Tail-Anchored Proteins 3 in Mycobacterium tuberculosis
Part of: Heran Darwin Lab |
UID: 10493
- Description
This study investigated the pathways important for Mycobacterium tuberculosis (M. tuberculosis) pathogenesis. M. tuberculosis genome was searched for open reading frames and an operon, Rv3679-Rv3680, was identified. Using structure prediction modeling, they found that Rv3679 and Rv3680 have some structural similarity to the guided entry of tail-anchored proteins 3, which delivers proteins into the membranes of the endoplasmic reticulum. The dataset contains coordinate and structure factor of ADP, ATPγS, and AMP-PNP. In addition, the publication includes supplementary data, which contains quantitative mass spectrometry data comparing proteins in total lysates of wild type, bagAB, and complemented M. tuberculosis strains.
DH5α
BL21(DE3)
H37Rv
MHD1428
MHD1385
MHD1431
Associated Publications
Data Type
Equipment Used
Software Used
Access
- Restrictions
-
Free to All
- Instructions
- The coordinate and structure factor files of ADP, ATPγS, and AMP-PNP are deposited in Protein Data Bank (PDB). All other relevant data are available on PubMed Central (PMC) under Supplementary Materials.
BioSpec Mini Bead Beater
SpeedVac
- Grant Support
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