The NYC Health and Nutritional Examination Survey (NYC HANES), modeled on the National Health and Nutrition Examination Survey (NHANES), is a population-based, cross-sectional study with data collected from physical examinations, clinical and laboratory tests, as well as face-to-face interviews and audio computer-assisted self-interviews (ACASI). It was first conducted in 2004 by the NYC Department...

Schizophrenic patients have a high rate of smoking and cognitive deficits which may be related to a decreased number or responsiveness of nicotinic receptors in their brains. Varenicline is a partial nicotinic agonist which is effects as an anti-smoking drug in cigarette smokers, although concerns have been raised about potential psychiatric side-effects. This data is from a double-blind placebo controlled...

This data was collected during clinical examinations at the NYU Comprehensive Epilepsy Center between the years of 2003 and 2008. Subjects included in this dataset have a confirmed epilepsy diagnosis from either routine electroencephalogram (EEG) or video-electroencephalogram (VEEG). The dataset does not include raw EEG data. There are 228 subjects in total. The following information was collected...

The Enhancing Neuroimaging Genetics through Meta-Analysis (ENIGMA) Consortium is a global project originating from University of Southern California which unites researchers across the fields of imaging genomics, neurology, and psychiatry to understand brain structure and function. ENIGMA consists of 50 active working groups which are organized into four major research cores: Genomics, Disease, Protocol...

The Upstate New York Infant Development Screening (Upstate KIDS) Study is a collaboration between the New York State Department of Health, University at Albany, and the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD). The study includes information from over 5,034 mothers and their 6,171 children in New York State, excluding New York City, who were recruited...

Previous studies in rodent showed impaired brain insulin signaling with resultant insulin resistance (IR) modulates synaptic plasticity and the corresponding behavioral functions. This study investigated whether brain enriched exosomes and brain IR differ between subjects with major depressive disorder (MDD) and respective controls. They also examined potential sex differences in circulating brain...

This study identified biological targets in major depressive disorder (MDD). Acetyl-l-carnitine (LAC), which is critical for hippocampal function and several behavioral domains, has rapid and enduring antidepressant like effects in LAC deficient rodents. As a result, this study examined LAC levels in humans. Following an initial phone screen, potential participants were evaluated in person to determine...

This dataset was collected for a study which examined differences in the gut microbiome within a cohort of 12-month old infants who provided samples either before the start of the COVID-19 pandemic or during the first 9 months of the pandemic. The study also assessed the demographics and health of the infants' primary caregivers, including factors such as race, ethnicity, socioeconomic status, mental...